Re: Very low dose of propecia EOD + IH Top 3?

[albe]

One of the reasons I chose Arimidex over DIM, was that I'm not so sure that it will help with estrogen dominance. I've only found a few studies. From what I've found it improves the ratio of 2-OHE1(weaker) to 16alpha-2OH1(stronger), but it does this by raising 2-OHE1 significantly without decreasing 16alpha-2OH1 significantly. I may be mistaken, but it seems like DIM might have an overall estrogenic effect. I included a study below.
http://www.ncbi.nlm.nih.gov/pubmed/15623462

In addition, having tested PM out extensively, I feel that it has an estrogenic effect, and is bad for hair. I'd be open to taking it again if I were proved wrong, but I'd need to see some evidence beforehand. With phytoestrogens in general they either displace stronger estrogens enough to help with estrogen dominance, or they have an overall estrogenic effect. Before hormonal profiles are performed for pueraria mirifica (and I've looked online to no avail), we can't be sure exactly what PM is doing.

After a lot of reading, I've jumped firmly on the bandwagon that excess estrogen is somehow very bad for hair. After 6 months on a regimin of PM and lavender I've gone from a thick nw2, to clearly diffusing in an nw7 pattern (which is strange and disconcerting given that none of my relatives have gone past nw4 or so). I'm still undecided and confused about the usefulness of topical estrogen (provided it doesn't have a systemic effect).

I actually found some pretty impressive regrowth pictures earlier from somebody who had tried arimidex and proscar in conjunction. I found this after I had ordered the arimidex.
http://www.hairsite.com/hair-loss/forum_entry-id-4011-page-0-category-5-order-last_answer.html

I don't really like the idea of using hardcore pharmaceuticals to tackle these issues, but I haven't found any natural substances with enough studies to support their efficacy. My hypothesis is that xenoestrogens are causing additional estrogen dominance that's not showing up on hormone tests, and that the average man would benefit by cutting their estrogen with an aromatase inhibitor.

[CausticSymmetry]

I was asked about finasteride problems today and it rekindled something that was mentioned only once in this forum so I think it deserves more mention.

Finasteride and I believe also Dutasteride use bromide to manfacture it, which is a halogen that disrupts iodine uptake to the thyroid. Since the tests to "prove" that blocking DHT doesn't cause low thyroid are only 6 months in length and since only some parameters are used to assume this, it is probably untrue.

[albe]

I remember you saying that.

My hope is that a high dose of lugol's/iosil should be enough to counteract the bromide, if any is left. Especially if you avoid other foods containing bromide (like bread).

[Jimboy]

Hey there!

about tamoxifen & Co. I'm really scared to try this out. I'm 20 years old, i don't want to do this combo for 5-6 years and then stop it. Who knows what will happen?

[CausticSymmetry]

I wouldn't touch of any of the chemicals either. I've observed one thing that is unshakable in medicine that drugs do and will cause side effects some of which cause irreversible changes if taken long enough.

As far as DIM goes, it's very safe and protects against the negative effects of estrogen in three ways.
It helps reduce the risks of lung cancer, prostate cancer and many others. It inhibits DHT, MMP-9 and some
users report helping to trim fat. Is this regulated estrogens negatively, then weight gain would be a side effect instead.

[sublime9]

nice! why do you take such a low dose of fin? did you get sides from a higher dose and do you get sides from it with the small dose?

As albe noted there is little difference between .25mg and 1mg of fin in regards to hair regrowth. That information is taken from a study performed in Japan that was very insightful. I did have some sides on fin although IH's regimen took care of most of those.

[danmrtini]

IH- Are the 7-hmr Lignans supposed to do what DIM does? Sounds like DIM does it without the sides.

[danmrtini]

Propecia, while lowering DHT, spikes Testosterone when you first start using it by as much as 20% I have read. This may be a reason some people get a shed and why acne becomes a big thing until levels stabilize. Wondering if using DIM or Lignans would attack that as well.

[CausticSymmetry]

danmrtini - I have tried both alone and together and I wasn't able to tell one way or the other. They do have totally different mechanisms.