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Question about natural androgen receptor blockers

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Question about natural androgen receptor blockers

Post  sizzlinghairs on Mon Dec 21, 2015 1:14 pm

To anyone in the know:

My question is about all natural androgen blockers, but specifically in regards to EGCG found in green tea.

So: does a compound like EGCG, which has been shown to blunt androgen activity, do so only under inflammatory circumstances, such as tumor growth? Or does it do it across the board, irregardless of the circumstance? Such as blocking positive for our body androgen functions? (libido, etc)

Much thanks to anyone in the know!

:PS: here is the study which shows it blunts androgen activity: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058706/

Androgen deprivation therapy is the major treatment for advanced prostate cancer (PCa). However, it is a temporary remission, and the patients almost inevitably develop hormone refractory prostate cancer (HRPC). HRPC is almost incurable, although most HRPC cells still express androgen receptor (AR) and depend on the AR for growth, making AR a prime drug target. Here, we provide evidence that epigallocatechin-3-gallate (EGCG), the major polyphenol in green tea, is a direct antagonist of androgen action.

sizzlinghairs

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