Search
 
 

Display results as :
 


Rechercher Advanced Search

Check Out Our Sponsors
Brought to you by
Hair Loss Forum
Navigation
 Portal
 Index
 Memberlist
 Profile
 FAQ
 Search
Navigation
 Portal
 Index
 Memberlist
 Profile
 FAQ
 Search

lower expression of vitamin D receptors in male pattern baldness

View previous topic View next topic Go down

lower expression of vitamin D receptors in male pattern baldness

Post  alphadelta on Wed Aug 10, 2016 5:17 pm

Assessment of vitamin D receptors in alopecia areata and androgenetic alopecia.
Abstract
BACKGROUND:
Alopecia areata (AA) is a frequent autoimmune disease, the pathogenesis of which is still unknown. Androgenetic alopecia (AGA) is a noncicatricial type of patterned hair loss. Expression of vitamin D receptors (VDRs) on keratinocytes is essential for maintenance of normal hair cycle, especially anagen initiation.

OBJECTIVE:
To assess VDRs in the skin and blood of AA and AGA patients, in order to evaluate their possible role in these hair diseases.

METHODS:
This study recruited 20 patients with AA, 20 patients with AGA, and 20 healthy controls. Blood samples and lesional scalp biopsies were taken from all participants for detection of VDR levels.

RESULTS:
Serum and tissue VDR levels were lower in AA as well as AGA patients when compared to controls (P = 0.000). Serum and tissue VDR were positively correlated in each group. Tissue VDR was significantly lower in female patients with AA than males (P = 0.046) although serum and tissue VDR levels were significantly higher in female AGA patients than males (P = 0.004).

CONCLUSION:
This study suggests an important role for VDR in the pathogenesis of AA and AGA through documenting lower serum and tissue VDR levels in AA and AGA patients in comparison with controls.


alphadelta

Posts : 169
Join date : 2011-10-12

View user profile

Back to top Go down

Re: lower expression of vitamin D receptors in male pattern baldness

Post  SoloDomo on Wed Sep 14, 2016 6:04 am

Bump

would supplemental vitamin D help??

SoloDomo

Posts : 24
Join date : 2016-01-27

View user profile

Back to top Go down

Re: lower expression of vitamin D receptors in male pattern baldness

Post  johndoe1225 on Wed Sep 14, 2016 6:06 am

SoloDomo wrote:Bump

would supplemental vitamin D help??

Probably wouldn't hurt:

http://www.hairloss-research.org/UpdateVitaminD3IronB12Combo.12-13.html

johndoe1225

Posts : 973
Join date : 2015-05-21

View user profile

Back to top Go down

Re: lower expression of vitamin D receptors in male pattern baldness

Post  CausticSymmetry on Wed Sep 14, 2016 6:26 am

Yes, absolutely, I've been doing this since 2006.


_________________
My regimen
http://www.immortalhair.org/mpb-regimen

Now available for consultation (hair and/or health)
http://www.immortalhair.org/health-consultation
avatar
CausticSymmetry
Admin

Posts : 11918
Join date : 2008-07-09

View user profile http://www.immortalhair.org/

Back to top Go down

Re: lower expression of vitamin D receptors in male pattern baldness

Post  johndoe1225 on Wed Sep 14, 2016 6:40 am

CausticSymmetry wrote:Yes, absolutely, I've been doing this since 2006.


How much daily? I hear 5,000 IU is a good number, but I also read that the only way to be sure is to monitor your blood levels routinely.

johndoe1225

Posts : 973
Join date : 2015-05-21

View user profile

Back to top Go down

Article...

Post  CampOfDavid on Wed Sep 14, 2016 6:45 am

Interesting read (article below). The conclusion is basically that if you are going to supplement with vitamin D you also should supplement with vitamin K2, vitamin A and magnesium.
http://www.precisionnutrition.com/stop-vitamin-d
avatar
CampOfDavid

Posts : 81
Join date : 2016-03-22

View user profile

Back to top Go down

Re: lower expression of vitamin D receptors in male pattern baldness

Post  Hairbeback on Wed Sep 14, 2016 5:54 pm

Why can't we do it through food?

Hairbeback

Posts : 733
Join date : 2009-04-02

View user profile

Back to top Go down

Re: lower expression of vitamin D receptors in male pattern baldness

Post  johndoe1225 on Thu Sep 15, 2016 1:51 am

Hairbeback wrote:Why can't we do it through food?

I think sun exposure is the best way (without considering UV rays and skin cancer etc), but in my opinion, considering modern lifestyles of being indoors most of the time, it's really hard to get such an amount from foods.

johndoe1225

Posts : 973
Join date : 2015-05-21

View user profile

Back to top Go down

Re: lower expression of vitamin D receptors in male pattern baldness

Post  Sage 1 on Thu Sep 15, 2016 7:31 am

So the recommendation of 1000 IU is far from correct?
Eat some mushrooms/oily fish with some dark leafy greens, to cover the whole vitamin spectrum.

Sage 1

Posts : 432
Join date : 2015-04-30

View user profile

Back to top Go down

Re: lower expression of vitamin D receptors in male pattern baldness

Post  johndoe1225 on Thu Sep 15, 2016 8:29 am

Sage 1 wrote:So the recommendation of 1000 IU is far from correct?
Eat some mushrooms/oily fish with some dark leafy greens, to cover the whole vitamin spectrum.

In the U.S., last I heard, it was like 600 IU daily, lol, but lots of people keep saying that's extremely low.

johndoe1225

Posts : 973
Join date : 2015-05-21

View user profile

Back to top Go down

Re: lower expression of vitamin D receptors in male pattern baldness

Post  NYJets on Thu Sep 15, 2016 3:42 pm

CausticSymmetry wrote:Yes, absolutely, I've been doing this since 2006.


I have some D3 that is sourced from Lanolin - throw it out or is it ok ? Thanks CS.
avatar
NYJets

Posts : 457
Join date : 2012-05-17

View user profile

Back to top Go down

Topical?

Post  CampOfDavid on Fri Sep 16, 2016 4:08 am

Do you think vit D in or as a topical would be any benefit?
avatar
CampOfDavid

Posts : 81
Join date : 2016-03-22

View user profile

Back to top Go down

Re: lower expression of vitamin D receptors in male pattern baldness

Post  Sponsored content


Sponsored content


Back to top Go down

View previous topic View next topic Back to top

- Similar topics

 
Permissions in this forum:
You cannot reply to topics in this forum