Glucose-6-Phosphate Dehydrogenase Deficiency and Physical and Mental Health until Adolescence.

View previous topic View next topic Go down

Glucose-6-Phosphate Dehydrogenase Deficiency and Physical and Mental Health until Adolescence.

Post  CausticSymmetry on Thu Nov 10, 2016 6:43 pm

PLoS One. 2016 Nov 8;11(11):e0166192. doi: 10.1371/journal.pone.0166192. eCollection 2016.
Glucose-6-Phosphate Dehydrogenase Deficiency and Physical and Mental Health until Adolescence.
Kwok MK1, Leung GM1, Schooling CM1,2.

BACKGROUND:
To examine the association of glucose-6-phosphate dehydrogenase (G6PD) deficiency with adolescent physical and mental health, as effects of G6PD deficiency on health are rarely reported.
METHODS:
In a population-representative Chinese birth cohort: "Children of 1997" (n = 8,327), we estimated the adjusted associations of G6PD deficiency with growth using generalized estimating equations, with pubertal onset using interval censored regression, with hospitalization using Cox proportional hazards regression and with size, blood pressure, pubertal maturation and mental health using linear regression with multiple imputation and inverse probability weighting.
RESULTS:
Among 5,520 screened adolescents (66% follow-up), 4.8% boys and 0.5% girls had G6PD deficiency. G6PD-deficiency was not associated with birth weight-for-gestational age or length/height gain into adolescence, but was associated with lower childhood body mass index (BMI) gain (-0.38 z-score, 95% confidence interval (CI) -0.57, -0.20), adjusted for sex and parental education, and later onset of pubic hair development (time ratio = 1.029, 95% CI 1.007, 1.050). G6PD deficiency was not associated with blood pressure, height, BMI or mental health in adolescence, nor with serious infectious morbidity until adolescence.
CONCLUSIONS:
G6PD deficient adolescents had broadly similar physical and mental health indicators, but transiently lower BMI gain and later pubic hair development, whose long-term implications warrant investigation.

_________________
My regimen
http://www.immortalhair.org/mpb-regimen

Now available for consultation (hair and/or health)
http://www.immortalhair.org/health-consultation
avatar
CausticSymmetry
Admin

Posts : 11887
Join date : 2008-07-09

View user profile http://www.immortalhair.org/

Back to top Go down

View previous topic View next topic Back to top

- Similar topics

 
Permissions in this forum:
You cannot reply to topics in this forum