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Question about "natural" 5AR inhibitors

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Question about "natural" 5AR inhibitors

Post  Benjamin Button on Thu Mar 23, 2017 9:54 am


So I just got a marketing email from "william hartfield" touting the benefits of ecklonia cava for hairloss stating that "In fact, its inhibitory effect was similar to finasteride"...

now I'm concerned because I wouldn't touch finasteride because I think androgens are really important for men. I've read CS saying that natural 5ar inhibition is somehow different to the gene suppression action of synthetic 5ar inhibitors.... But I don't get it. 5ar inhibition is 5ar inhibition, how is it different?

If anybody can clarify this, that would be great.
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Re: Question about "natural" 5AR inhibitors

Post  CausticSymmetry on Fri Mar 24, 2017 2:56 am

Benjamin Button wrote:
So I just got a marketing email from "william hartfield" touting the benefits of ecklonia cava for hairloss stating that "In fact, its inhibitory effect was similar to finasteride"...

now I'm concerned because I wouldn't touch finasteride because I think androgens are really important for men. I've read CS saying that natural 5ar inhibition is somehow different to the gene suppression action of synthetic 5ar inhibitors....  But I don't get it. 5ar inhibition is 5ar inhibition, how is it different?

If anybody can clarify this, that would be great.

I take Ecklonia Cava for many reasons, although the 5-AR reduction (meaning adding an extra electron) is not the most important reason, however that's exactly how it works to do that. The way finasteride "works" is quite a bit different, it acts on a gene level that suppresses that enzyme unnaturally too long, and this is partially why it creates side-effects.

I have a little bit more info on ECE and DHT in this article.

http://longevitypost.com/stop-fearing-testosterone-dht/

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Re: Question about "natural" 5AR inhibitors

Post  Benjamin Button on Fri Mar 24, 2017 3:34 am

Thanks for the response man, your awesome! I appreciate you takin the time to answer, and as soon as I can afford labs and a proper consult I will.

..But anyway, ecklonia cava and possibley other natural 5-ar inhibitors do something different to the enzyme to inhibit it. If I understand correctly, they are possibly just temporarily putting some of the enzyme out of action by adding an electron.. which can presumably then "come back to life" when that electron is removed by something else later. And the overall result will be that 5ar function is lowered to healthy levels in an easily reversible way that is typical of natural foods affects on the body. (sorry about being long winded here, just wanna understand.)

whereas finasteride just comes in and completely halts all 5ar activity, sometimes irreversibley, by some other mechanism that would not be typical of natural human diet..

right... then 5ar inhibition is not simply 5ar inhibition after all. I will get back on ecklonia cava so.


Follow up Question having read the linked article... Why the hell am I so sensitive to dht? I have a thick beard, hairy back, and am in a war against aggressive hairloss at 31 years old. I've made serious gains and set backs, but I think I am perhaps an individual that has that sensitivity issue as a primary factor...
should I be trying to upregulate SHBG somehow? Scratch that, It's probably on its way up now anyway as I age.

Am I overexpressing androgen receptors? yes.

Why? is that the genetic component, I have more androgen receptors. Can I do something to correct that?
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Re: Question about "natural" 5AR inhibitors

Post  CausticSymmetry on Sun Mar 26, 2017 5:24 am

Sorry for my late reply. Natural 5-AR inhibitors work differently or by various mechanisms.

My least favorite type of natural 5-AR inhibitor for instance I think is only appropriate for people who are in late adolescence or early 20's, such as Beta Sitosterol (there are other types also), they bind testosterone in the gut (and also the source/cholesterol). This form really loses effectiveness and it can contribute to poor performance in the bedroom.

Ecklonia Cava does a lot more than add electrons or naturally reduce 5-AR, because it also helps arrest inflammation that promotes higher 5-AR levels as well, plus it stimulates the growth factors necessary for hair growth, meanwhile boosting circulation.

Finasteride creates an imbalance of type 1 and type 2 5-AR, and also long-term suppression of neurosteroids in the brain contributes to anxiety and depression. Inhibiting 5-AR by "chemical castration" can create an imbalance (feed-back loop issue) that some people really struggle to recover from. Some can get away with it smoothly after they stop, but some will continue to experience problems. So it's a form of Russian roulette.

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Re: Question about "natural" 5AR inhibitors

Post  Benjamin Button on Wed Apr 12, 2017 9:53 am

Rob of perfect hair health has just written an essay on this topic for those who want to hear a little more on the finasteride vs natural DHT differences.

https://perfecthairhealth.com/natural-dht-blockers-vs-finasteride-they-all-cause-sexual-side-effects/
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