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Rebuilding the gut lining

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Rebuilding the gut lining

Post  hair grower on Mon Nov 30, 2009 11:29 pm

Hey guys

I'm about to embark on a program to rebuild and strengthen the gut lining. My plan is to rotate some of the probiotic strains that LittleFighter has recommended, mainly the s. boulardii, plantarum 299v and the LGG. Another foundation could be the higher doses of L-Glutamine. I'm also thinking of these products:

Butyr-aid, http://www.iherb.com/Allergy-Research-Group-Nutricology-ButyrAid-100-Tablets/8510?at=0

PepZinGl, http://www.iherb.com/PepZinGl-120-Veggie-Caps/2467?at=0

Anyone have any experience with these two? And for the experienced posters here, do you know of any other products that would be of benefit to heal the gut lining?

I'm also going to fight candida and dysbiosis using Waiora NCD, garlic, different natural yeast killers (such as oregano oil, GSE etc.), maybe some mms when off the Waiora zeolites and, off course, anticandida diet.

Thanks!

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Re: Rebuilding the gut lining

Post  LittleFighter on Tue Dec 01, 2009 12:33 am

hair grower,

I have tested both. Pepzin GI is probably mostly helpful for ulcers in the stomach, I think the dose isn't enough to reverse leaky gut. I used butyraid, but caused me die-off and mild diarreah if I took it on an emtpy stomach. With my current progress I might be able to tolerate it... I still have a full bottle of it. BTW probiotics themselves, produce butyrate and other useful fatty acids when they ferment different carb's.

Things I currenlty use and help the most:

- A few grams of Glutamine 10-20 gms a day in divided doses, on an empty stomach (helps rebuild tissue and with SIgA); Glutamine can heal stomach ulcers by itself in a couple of weeks
- Whey protein (Jarrow's is good)
- LGG, L. P. 299v, boulardii
- Anti-fungals (seek a formula that provides oregano, garlic, berberine, etc.); oregano is the most powerful of all of them, try to take them away from probiotics
- Digestive enzymes (plant-based), betaine hcl + pepsin, with each meal; this way you can reduce fermentation, undigested matter, bad bacteria and more.

Other things to add is magnesium glycinate (take enough, 600 mg at least), l-optizinc (30 mg or more), omega-3's (EPA/DHA), Vitamin A (helps with SIgA and tissue regeneration). A natural source of nutrients like Brewer's Yeast will certainly help too.

I would also recommend you to drop wheat and casein, at least for a while.

Remember this, because it is crusial: Keep the healing process for a few months; it is very common to make the mistake of dropping the treatment because IT TAKES TIME TO HEAL COMPLETELY and sometimes to see progress. For the first time in my life, I'm sticking with the treatment and I'm seeing TRUE improvements!

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Re: Rebuilding the gut lining

Post  Paradox on Tue Dec 01, 2009 2:15 am

Little Fighter,

Are you trying to avoid glutamate? I ask because there is a lot of glutamic acid in protein powders. I stopped taking my whey for this reason. I'm hyper-sensitive to glutamate right now as I'm tapering off medication. Do you take anything to balance glutamate/gaba. metagenics has a product called Trancor I was using with b6, mag, NAC, green tea cachethins (spelling?), and taurine. It was expensive so I just bought some NOW p-5-p with mag and b2 to try for a replacement.

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Re: Rebuilding the gut lining

Post  Paradox on Tue Dec 01, 2009 2:17 am

BTW I'm not taking brewers yeast for the same reason. I wish I could take both for more energy and muscle mass from working out.

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Re: Rebuilding the gut lining

Post  scottyc33 on Tue Dec 01, 2009 3:09 am

Littlefighter,

I bought some Saccharomyces Boulardii and LGG at your recommendation.

My question is should I take one before the other? Should I take both at the same time?
Does it matter?

Thanks.

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Re: Rebuilding the gut lining

Post  Paradox on Tue Dec 01, 2009 5:17 am

Scottyc33,

I don't mean to speak for LF but I am doing the same protocol from this article that he posted here: http://www.nutricology.com/Oct-2009-In-Focus-Newsletter-Probiotics-Can-Shift-Mood-sp-97.html

To answer your question....In the article the protocol is to use the S.B. first for a couple months to raise SiGa levels enough to introduce other bacteria. After the S.B., is when the LGG is taken. It's a great article, but I believe LF said he is taking S.B. and LGG at the same time from what I can remember. I'll let him speak on that.

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Re: Rebuilding the gut lining

Post  CausticSymmetry on Tue Dec 01, 2009 5:33 am

I'm not so sure that some varieties of brewer's yeast are a risk, such as Now Brand, as it doesn't appear to contain any free-form amino acids. Because the barley is fermented to me it would minimize the risk--of course I could be wrong but just saying.

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Re: Rebuilding the gut lining

Post  Paradox on Tue Dec 01, 2009 6:32 am

That's interesting CS. So you are saying that it's not as simple as just reading the label for glutamic acid content? I'll have to take a look at the Lewis Labs BY I have. I was taking it for a while until I picked up on the glutamic acid being like 2 plus grams. My Doctor took me off glutamine because it can convert to glutamate so I figured if I was going to that extreme I might as well toss the brewer's yeast as well. She recommended N-A-G as an alternative to glutamine BTW, and I've been taking that for gut health. I didn't know N-A-G was a precursor to Hyaluronic acid, but it says so on the bottle. Talk about tangents...sorry

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Re: Rebuilding the gut lining

Post  kijumn on Tue Dec 01, 2009 7:34 am

I don't mean to answer for CS but Brewers Yeast should be one of the very last food sources to be removed regarding "free" glutamic acid. The reason being the B vitamin such as B6, B12, niacin, etc is "very" helpful. If you're worried about oxalates in the beets from Lewis Labs taking a food that contains calcium you should be fine.

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Re: Rebuilding the gut lining

Post  CausticSymmetry on Tue Dec 01, 2009 9:12 am

JHarsh80 - Interesting, I was just looking at Lewis Labs and see that they list all those amino acids. However, it is unlikely that they are in free-form, so as a complete protein it should be safe.

If you look at Now brand, there's no mentioned of the amino acids at all, but they are certainly there, just as complete protein, not fractionated.

In any case both use just brewer's yeast as the only ingredient.

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Re: Rebuilding the gut lining

Post  Paradox on Tue Dec 01, 2009 8:22 pm

jdp710 wrote:I don't mean to answer for CS but Brewers Yeast should be one of the very last food sources to be removed regarding "free" glutamic acid. The reason being the B vitamin such as B6, B12, niacin, etc is "very" helpful. If you're worried about oxalates in the beets from Lewis Labs taking a food that contains calcium you should be fine.

I honestly am not familiar with oxalates, but I do take NOW's 'Adam' men's multivitamin so I am getting synthetic b's. Some are the methylated form like b12, and b6. I just ordered some more p-5-p (b6) to take later in the day. I am coming off psych meds and trying to limit anything that is going to create an excitatory response, i.e. glutamate. I have a feeling that some b's don't get along well with me in that regard while others do. It seems I almost feel more relaxed when I don't take the multi. That may not entirely be from the b's but other things in it like choline maybe?

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Re: Rebuilding the gut lining

Post  Paradox on Tue Dec 01, 2009 8:30 pm

CS,

I noticed that as well. I admit that I'm not really sure why a complete protein with a certain level of glutamic acid would be less 'bad' than free form amino acids? If that is the case, would I be ok to take the 100% whey isolate again without risking any unwanted psychological effects as a result?

I read recently that the glutamic acid is a result from anything that has been hydrolyzed and that is why it is found in protein powders. It was on a web site for some special protein made from peas and rice I believe. I didn't bookmark it. I'd like to go back on the whey and the BY, but I don't want to risk a 'reaction' or increase my benzo withdrawal symptoms by doing so. I don't feel like my understanding of this subject is close to 100% so I'm hesitant to risk it.

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Re: Rebuilding the gut lining

Post  CausticSymmetry on Tue Dec 01, 2009 8:56 pm

JHarsh80 - Check out Jarrow Brand, you'll see why:

http://www.iherb.com/Whey-Protein-Unflavored-2-lbs-908-g/343?at=0

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Re: Rebuilding the gut lining

Post  kijumn on Tue Dec 01, 2009 9:10 pm

JHarsh80,

Here is a quote from Battling the "MSG Myth." I'd highly recommend this book if you are in fact MSG/free glutamic acid sensitive

"Whey - When cheese is produced, milk is treated with enzymes and heated to separate the curds from the whey, which is a liquid high in protein. Some glutamate may be freed up by the heat and enzyme activity, but when whey is further processed and then dried to a powder, it will contain more concentrations of free glutamate. It is then bagged and sold as a food product to be used in the manufacture of many products such as ice cream, crackers, boxed macaroni and cheese, and candy. The more whey is processed, such as in whey protein or whey protein isolate, the more glutamate it will likely contain. Sometimes hydrolyzed milk solids are added, making it even higher in glutamate. When a label says "whey", it may contain any of the whey products. Dry whey or dry milk solids are added to low fat milk to give it more creaminess. Since milk is naturally high in glutamate, many severely sensitive individuals avoid or go easy on all dairy products."

... when "milk" appears on the label, it means dry milk."

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Re: Rebuilding the gut lining

Post  Paradox on Wed Dec 02, 2009 12:42 am

CausticSymmetry wrote:JHarsh80 - Check out Jarrow Brand, you'll see why:

http://www.iherb.com/Whey-Protein-Unflavored-2-lbs-908-g/343?at=0

CS, I read the description and it states that hydrolyzation decreases glutamine content. This makes it more confusing to me because I still don't understand why that is significant considering that glutamine can be metabolized to glutamate and vice-versa. I'm still confused as to why glutamic acid in complete protein is different than in non-complete. This is from wikipedia on glutamate-glutamine cycle:

In biochemistry, the glutamate-glutamine cycle is a sequence of events by which an adequate supply of the neurotransmitter glutamate is maintained in the central nervous system.[1]

Initially, glial cells release glutamine, which is then taken up into presynaptic terminals and metabolized into glutamate by glutaminase (a mitochondrial enzyme). Glutamate can also be produced by transamination of 2-oxoglutarate, an intermediate in the Citric acid cycle.[1]

The glutamate that is synthesized in the presynaptic terminal is packaged into synaptic vesicles by the transporter VGLUT. Once the vesicle is released, glutamate is removed from the synaptic cleft by excitatory amino acid transporters (EAATs), of which there are five types. Glutamate taken up by glial cells is then converted into glutamine by glutamine synthetase, and transported out of the cells into the nerve terminal. This allows synaptic terminals and glial cells to work together in order to maintain a proper supply of glutamate.[1]

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